ECOG: The Eastern Cooperative Oncology Group

ECOG Protocols Active as of 03/11/10

Click on the protocol number to view the NCI's PDQ description of the protocol.


LEUKEMIA COMMITTEE


ProtocolTitle
10403 An Intergroup Phase II Clinical Trial for Adolescents and Young Adults with Untreated Acute Lymphoblastic Leukemia (ALL)
Activation Date: 14-may-2008
10404 A Genetic, Risk-Stratified Randomized Phase II Study of Four Fludarabine/Antibody Combinations for Patients with Symptomatic, Previously Untreated Chronic Lymphocytic Leukemia
Activation Date: 14-may-2008
CALGB10603 A Phase III Randomized, Double-Blind Study of Induction (Daunorubicin/Cytarabine) and Consolidation (High-Dose Cytarabine) Chemotherapy + Midostaurin (PKC412) or Placebo in Newly Diagnosed Patients < 60 Years of Age with FLT3 Mutated Acute Myeloid Leukemia (AML)
Activation Date: 22-apr-2008
E1902 A Phase II Study of Reduced Intensity Allogeneic Stem Cell Transplant for the Treatment of Myelodysplastic Syndromes
Activation Date: 18-may-2005 Suspended: 23-sep-2009
ECOG Participants(requires Adobe Acrobat)
E1904 A Phase II Study of MOAD (Methotrexate, Vincristine, L-asparaginase, and Dexamethasone) with Subcutaneous Campath (NSC 715969) for Adults with Relapsed or Refractory Acute Lymphocytic Leukemia (ALL)
Activation Date: 29-jun-2006
ECOG Participants(requires Adobe Acrobat)
E1905 A Randomized Phase II Trial of Azacitidine with or without the Histone Deacetylase Inhibitor Entinostat for the Treatment of Myelodysplastic Syndrome,Chronic Myelomonocytic Leukemia (Dysplastic Type), and Acute Myeloid Leukemia with Multilineage Dysplasia
Activation Date: 18-aug-2006
E1906 A Phase II Randomized Trial of Carboplatin and Topotecan; Flavopiridol, Mitoxantrone and Cytosine Arabinoside; and Sirolimus, Mitoxantrone, Etoposide and Cytosine Arabinoside for the Treatment of Adults with Primary Refractory or Initial Relapse of Acute Myelogenous Leukemia(AML) (Limited institution participation)
Activation Date: 16-oct-2008
E2903 Phase II Trial of Pentostatin, Cyclophosphamide, and Rituximab (PCR) Followed By Campath-1H For Previously Treated Relapsed or Refractory Patients With Chronic Lymphocytic Leukemia
Activation Date: 16-dec-2004
ECOG Participants(requires Adobe Acrobat)
E2905 Randomized Phase III Trial Comparing the Frequency of Major Erythroid Response (MER) to Treatment with Lenalidomide (Revlimid) Alone and in Combination with Epoetin Alfa (Procrit) in Subjects with Low- or Intermediate-1 Risk MDS and Symptomatic Anemia
Activation Date: 29-jan-2009
E3903 Ancillary Laboratory Protocol for Collecting Diagnostic Material on Patients Considered for ECOG Treatment Trials for Leukemia or Related Hematologic Disorders
Activation Date: 08-jul-2004
ECOG Participants(requires Adobe Acrobat)
S0521 A Randomized Trial of Maintenance Versus Observation For Patients With Previously Untreated Low and Intermediate Risk Acute Promyelomic Leukemia (APL), Phase III
Activation Date: 22-jan-2008
S0535 A Phase II Study of ATRA, Arsenic Trioxide, and Gemtuzumab Ozogamicin in Patients with Previously Untreated High-Risk Acute Promyelocytic Leukemia
Activation Date: 23-jun-2008

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Revised: 03/11/10